# asd-def ## Investigations ::::{grid} 1 1 2 2 :gutter: 3 :::{grid-item-card} 1. Reproducing the reference classes :link: packages/analysis/investigations/reproducing-the-reference-classes :link-type: doc Do the four classes reproduce on the release held here, and can they be named as the authors named them? ::: :::{grid-item-card} 2. Selecting the number of classes :link: packages/analysis/investigations/selecting-the-number-of-classes :link-type: doc How many classes do the data support, and do the selection criteria back the authors' choice of four? ::: :::{grid-item-card} 3. Stability under refitting :link: packages/analysis/investigations/stability-under-refitting :link-type: doc Do the classes survive re-initialisation and resampling, or are they an artefact of one fit or one sample? ::: :::{grid-item-card} 4. The minimum viable stratum size :link: packages/analysis/investigations/the-minimum-stratum-size :link-type: doc How small can a stratum be before four-class recovery breaks down, which bounds the stratification bins? ::: :::{grid-item-card} 5. Replicating in the SSC :link: packages/analysis/investigations/replicating-in-the-ssc :link-type: doc Do the four classes reappear in a second, independent cohort? ::: :::: ## Packages ::::{grid} 1 1 2 2 :gutter: 3 :::{grid-item-card} analysis :link: packages/analysis/index :link-type: doc Reproduce the Litman autism classes and test their stability across age at diagnosis and diagnostic era. ::: :::{grid-item-card} figures :link: packages/figures/index :link-type: doc Render the analysis artefacts as Matplotlib figures for the manuscript. ::: :::{grid-item-card} dscat :link: packages/dscat/index :link-type: doc A searchable catalogue over the versioned SPARK and SSC data dictionaries. ::: :::{grid-item-card} docs :link: packages/docs/index :link-type: doc Build and live-preview this Sphinx site. ::: :::: :::{toctree} :hidden: :maxdepth: 2 packages/analysis/index packages/figures/index packages/dscat/index packages/docs/index :::